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Types 16 and 18 of HPV are considered "high risk" because they can cause cancer and are responsible for 25% of CIN 1 lesions and 70% of CIN 2 and 3 lesions, and anogenital cancers. "Low risk" types 6 and 11 generally do not cause cancer but are associated with 25% of CIN 1 lesions and 90% of genital and anal warts.
